Ongoing research and areas of interest:
Assessment of novel lipoxin in the treatment of murine SLE (with Stan Louie, School of Pharmacy)
Role of B cells and BAFF in generation of T regulatory cells in non-autoimmune and SLE mice
Sex-based and race/ethnicity-based disparities in authorship in high-impact journals and in payments received from industry
Clinical trials:
Gilead: Protocol No. GS-US-417-0304: A Multicenter, Double-blind, Long Term Extension Study to Assess the Safety and Efficacy of Filgotinib in Subjects with Rheumatoid Arthritis. IRB: HS-17-00931.
Kiniksa: Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Assess the Safety, Pharmacokinetics, and Efficacy of KPL-404 in Subjects with Moderate to Severe, Active Rheumatoid Arthritis with Inadequate Response or Intolerance to at Least One Biologic Disease-modifying Anti-rheumatic Drug or a Janus Kinase Inhibitor, In IRB Review process.
Norvatis: CVAY736F12301: A randomized, double-blind, parallel group, placebo-controlled multicenter phase 3 study to evaluate efficacy, safety and tolerability of two regimens of ianalumab on top of standard-of-care therapy in patients with systemic lupus erythematosus (SIRIUS-SLE 1) In IRB Review process.
XBioTech: Phase II, Double-Blind, Placebo-Controlled, Randomized Trial Examining Natrunix Combination with Methotrexate for the Treatment of Rheumatoid Arthritis. In IRB Review process.
Selected Publications:
Delgado M, Rodman J, Xepoleas M, Weisman M, Wise LM. Differences in reproductive health discussions in an urban Hispanic population with SLE: lessons from the field. Lupus Sci Med. 2024 Feb 20;11(1):e001095. doi: 10.1136/lupus-2023-001095. Erratum in: Lupus Sci Med. 2024 May 8;11(1):e001095corr1. doi: 10.1136/lupus-2023-001095corr1. PMID: 38382933; PMCID: PMC10882303.
Arkfeld D, Gonzales SAB, Ruddy K. The Effect of Low-Dose Glucocorticoids Over Two Years on Weight and Blood Pressure in Rheumatoid Arthritis. Ann Intern Med. 2024 Apr;177(4):545. doi: 10.7326/L24-0003. PMID: 38621264.
Alhassan E, Yi BY, Rodman J, Weisman MH, Crew A, Wise L. Unique characteristics of anti-MDA-5 associated dermatomyositis in Southern California with a large Hispanic population. Semin Arthritis Rheum. 2024 Jun;66:152434. doi: 10.1016/j.semarthrit.2024.152434. Epub 2024 Mar 15. PMID: 38503149.
Alhassan E, Nguyen K, Hochberg MC, Mitchell BD. Causal Factors for Osteoarthritis: A Scoping Review of Mendelian Randomization Studies. Arthritis Care Res (Hoboken). 2024 Mar;76(3):366-375. doi: 10.1002/acr.25252. Epub 2024 Feb 7. PMID: 37846209; PMCID: PMC10922494.
Gonzales SA, Mortezaei K, Arkfeld D. Rituximab Induced Flare of Psoriatic Arthritis in a Patient with Devic's Syndrome: A Case Report. Curr Rheumatol Rev. 2024 Feb 29. doi: 10.2174/0115733971275981240221062257. Epub ahead of print. PMID: 38425114.
Alhassan E, Nguyen K, Hochberg MC, Mitchell BD. Causal Factors for Osteoarthritis: A Scoping Review of Mendelian Randomization Studies. Arthritis Care Res (Hoboken). 2024 Mar;76(3):366-375. doi: 10.1002/acr.25252. Epub 2024 Feb 7. PMID: 37846209; PMCID: PMC10922494.
Yazdany J, Ware A, Wallace ZS, Bhana S, Grainger R, Hachulla E, Richez C, Cacoub P, Hausmann JS, Liew JW, Sirotich E, Jacobsohn L, Strangfeld A, Mateus EF, Hyrich KL, Gossec L, Carmona L, Lawson-Tovey S, Kearsley-Fleet L, Schaefer M, Ribeiro SLE, Al-Emadi S, Hasseli R, Müller-Ladner U, Specker C, Schulze-Koops H, Bernardes M, Fraga VM, Rodrigues AM, Sparks JA, Ljung L, Di Giuseppe D, Tidblad L, Wise L, Duarte-García A, Ugarte-Gil MF, Colunga-Pedraza IJ, Martínez-Martínez MU, Alpizar-Rodriguez D, Xavier RM, Isnardi CA, Pera M, Pons-Estel G, Izadi Z, Gianfrancesco MA, Carrara G, Scirè CA, Zanetti A, Machado PM. Impact of Risk Factors on COVID-19 Outcomes in Unvaccinated People With Rheumatic Diseases: A Comparative Analysis of Pandemic Epochs Using the COVID-19 Global Rheumatology Alliance Registry. Arthritis Care Res (Hoboken). 2024 Feb;76(2):274-287. doi: 10.1002/acr.25220. Epub 2023 Nov 7. PMID: 37643903.
Shojaie L, Bogdanov JM, Alavifard H, Mohamed MG, Baktash A, Ali M, Mahov S, Murray S, Kanel GC, Liu ZX, Ito F, In GK, Merchant A, Stohl W, Dara L. Innate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors. Cell Death Dis. 2024 Feb 14;15(2):140. doi: 10.1038/s41419-024-06535-7. PMID: 38355725; PMCID: PMC10866933.
Gonzales SAB, Alexopoulos C, Arkfeld DG. Potential Benefits of Psilocybin for Lupus Pain: A Case Report. Curr Rheumatol Rev. 2024;20(1):97-99. doi: 10.2174/1573397119666230904150750. PMID: 37670693.
Stohl W, Parikh K. Industry Payments to United States Rheumatologist-Authors of Publications in High-Impact Rheumatology Journals. ACR Open Rheumatol. 2023 Nov;5(11):609-618. doi: 10.1002/acr2.11609. Epub 2023 Sep 7. PMID: 37675758; PMCID: PMC10642244.
Ward NKZ, Pal S, Ruddy K, Savvas S. Attitudes and beliefs towards COVID-19 and COVID-19 vaccination among rheumatology patients in a Los Angeles County safety net clinic. BMC Rheumatol. 2023 Jun 1;7(1):13. doi: 10.1186/s41927-023-00338-7. PMID: 37259135; PMCID: PMC10231953.